Table 3.
Distribution of vitamin B12, Homocysteine and Thiol parameters in the patient group according to gender and age
| Parameter | Male (n = 21) | Female (n = 24) | P1β | Age1*(n = 19) | Age2**(n = 12) | Age 3***(n = 14) | P2§ |
|---|---|---|---|---|---|---|---|
| Vitamin B12 (pg/ml) | 164.4 (94–211) | 178 (79–280) | 0.37 | 161.6 (94–256) | 168 (106–224) | 155 (79–280) | 0.60 |
| Homocysteine (µmol/L) | 35.8 (22.9–94.9) | 42.4 (23.5–86.5) | 0.09 | 38.6 (22.9–94.9) | 34 (23.4–57.1) | 44.8 (26.3–86.5) | 0.14 |
| Total Thiol (µmol/L) | 234.2 (275–594) | 478 (325–685) | 0.15 | 461.8 (298–685) | 462.4 (275–630) | 447.8 (305–658) | 0.88 |
| Native Thiol (µmol/L) | 383.8 (243–510) | 419.1 (266–608) | 0.19 | 405 (243–594) | 406 (245–578) | 396.2 (266–608) | 0.89 |
| Disulfide | 25.2 (14–44) | 29.5 (15–55) | 0.08 | 28.3 (20-45.5) | 28.2 (14–55) | 25.7 (15–43) | 0.52 |
| Disulfide/Native Thiol | 6.8 (3.6–14.6) | 7.4 (4.1–16.2) | 0.39 | 7.4 (4.1–14.6) | 6.9 (36-11.5) | 6.9 (4.1–16.2) | 0.69 |
| Disulfide/Total Thiol | 5.9 (3.4–11.3) | 6.3 (3.8–12.2) | 0.39 | 6.4 (3.8–11.3) | 6.1 (3.4–9.3) | 5.9 (3.8–12.2) | 0.68 |
| Native Thiol/Total Thiol | 88.1 (77.4–93.2) | 87.3 (75.6–92.4) | 0.37 | 87.2 (77.4–92.4) | 87.8 (81.4–93.2) | 88.2 (75.6–92.4) | 0.68 |
β= Mann-Whitney U test, §=Kruskal Wallis test
*Age 1 = The group of patients whose age is between 11–13 years; ** Age 2 = 14–15 years;***Age 3 = 16–17 years