Figure 2:

Flow diagram showing enrollment and allocation of subjects to treatment groups and observation during treatment for up to two years and prepared according to the guidelines specified in www.CONSORT-statement.org [41]. All 197 randomized subjects completed 4 baseline visits and provided blood and urine samples, and completed at least one of the three imaging tests (mammography, breast magnetic resonance imaging or bone density scan). Numbers of observations for various outcome analyses at the conclusion of the study are shown [32–34].