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Alignments of N-terminal portions of TNNI and TNNT genes. (A) Similar glutamic acid and proline-rich N-terminal extensions in predicted ancestral TNNI3 and TNNI5. Bolded text (serines) indicates protein kinase A target site in TNNI3 that is absent in TNNI5. (B) Comparison of TNNI3 and TNNI5 with ancestral TNNT (common ancestral sequence of TNNT1-4) also shows similarities in N-terminal extensions.
