Table 2.
Time × Group Analyses, Complete Sample
| Time Point | Factor | Hippocampus | Gray Matter | NAWM | WMHI | Accelerated Aging | Total Recall | |
|---|---|---|---|---|---|---|---|---|
| Baseline, 4-month follow-up | Time | F | 62.127 | 58.777 | 20.047 | 42.311 | 140.217 | 17.663 |
| P | <.001 | <.001 | <.001 | <.001 | <.001 | <.001 | ||
| Group | F | .002 | 3.374 | .315 | 1.980 | 3.287 | .778 | |
| P | .966 | .069 | .576 | .163 | .073 | .380 | ||
| Time × Group | F | 4.453 | .029 | .768 | .434 | .089 | 2.252 | |
| P | .037 | 0.866 | .383 | .512 | .766 | .137 | ||
| HA-PCI | n | 57 | 57 | 57 | 55 | 58 | 55 | |
| PCI | n | 46 | 46 | 46 | 44 | 46 | 41 | |
| Baseline, 4- and 12-month follow-up | Time | F | 77.611 | 16.501 | 71.091 | 18.399 | 47.22 | 1.521 |
| P | <.001 | <.001 | <.001 | <.001 | <.001 | .229 | ||
| Group | F | 1.072 | 2.806 | .004 | 1.905 | 2.749 | .098 | |
| P | .305 | .112 | .948 | .174 | .103 | .755 | ||
| Time × Group | F | 7.138 | 1.305 | 1.536 | 1.354 | .149 | .792 | |
| P | .002 | .280 | .225 | .268 | .862 | .459 | ||
| HA-PCI | n | 28 | 28 | 28 | 29 | 29 | 25 | |
| PCI | n | 27 | 27 | 27 | 23 | 27 | 23 |
Abbreviations: HA-PCI, hippocampal avoidance prophylactic cranial radiation; NAWM, normal-appearing white matter; WMHI, white matter hyperintensities.
Significant P values are displayed in bold.