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. 2023 Jan 7;13:361. doi: 10.1038/s41598-023-27593-5

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Regulatory networks of WLZYW components correspond to potential pruritus targets. (A) Schedule of Network Pharmacology. (B) Venn Diagram of Pruritus Targets. (C) The intersection of WLZYW components targets and pruritus targets. (D) WLZYW potential targets pool network. The light blue quadrilateral in the center represents 160 coincident targets of WLZYW and pruritus. The circles on each side represent the compounds, one color is one component. Visualization via Cytoscape 3.8.0.