Figure 2.

Conditional disorder in MobiDB. MobiDB entry page of the human Paxillin protein, accession P49023. On the left, the ‘AlphaFold-structure (pLDDT)’ (top) and ‘AlphaFold-disorder (RSA)’ (bottom) features, representing high-confidence well-structured regions (cyan) and exposed residues (red), respectively. On the right, the predicted LIPs (violet), resulting from the intersection between the two sets of residues highlighted on the left. The screenshots are taken from the ‘Disorder’ tab (left) and from the ‘Binding’ tab (right) of the entry page. Residue annotations are calculated with the AlphaFold-disorder script (26) applied to AlphaFoldDB predictions.