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. 2022 Nov 18;51(D1):D395–D402. doi: 10.1093/nar/gkac1013

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© The Author(s) 2022. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Ligand info page. The Ligands subsection of GPCRdb has been extended to 211 320 ligands and 466 278 binding affinity or potency values from the ChEMBL (16), Guide to Pharmacology (15) or PDSP K_i databases (https://pdsp.unc.edu/databases/kidb.php). The new ligand info page shows ligand structure, names, chemical properties, molecule type, drug status, and endogenous/surrogate status, and database links. When available, GPCR-ligand crystal/cryo-EM structure complexes and mutations affecting ligand activity are also shown. Bioactivities across receptor targets are shown in the browser at the bottom.