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. 2022 Nov 29;51(D1):D1405–D1416. doi: 10.1093/nar/gkac1033

Table 2.

UpSet chart example table

List description How to generate that list Which filter to use Question
Figure 5A List of active ligands for a target of interest Link on target details page Target What compounds will activate my target, and not some others I want to distinguish between?
Figure 5B All targets Go to target list page NIH target lists Which targets left the IDG list in 2022?
Figure 5C All targets Go to target list page Data source Which targets are in the Pro-Kino database, but not Dark Kinase Knowledgebase?
Figure 5D Any target list Generate an interesting target list—see Materials and Methods PANTHER class/DTO class Which of these targets is involved in RNA binding, but no DNA binding?

A table of examples of interesting questions that can be addressed through the use and interpretation of the UpSet charts in Pharos.

The columns provide a description of the list, a brief description of how to generate such a list, the filter to construct the UpSet plot for, and the question that can be addressed by it.

Images in Figure 5 show the corresponding UpSet plot for these examples.