Table 1.

Notable improvements in BV-BRC that either did not exist in PATRIC, IRD/ViPR, or both prior to the merger

	PATRIC	IRD/ViPR	BV-BRC
Data types
Domains and motifs	No	Yes	Yes
Epitopes	No	Yes	Yes
Protein structures	No	Yes	Yes
Surveillance and serology	No	Yes	Yes
Services
Assembly (de novo)	Yes	No	Yes
SARS-Cov-2 assembly and annotation	No	No	Yes
SARS-CoV-2 variant tracking	No	No	Yes
Similar genome finder	Yes	No	Yes
Meta-CATS	No	Yes	Yes
Whole genome alignment	Yes	No	Yes
Primer design	No	Yes	Yes
Gene tree (user-selected genes/proteins)	No	Yes	Yes
Proteome comparison	Yes	No	Yes
Taxonomic classification	Yes	No	Yes
Metagenomic binning	Yes	No	Yes
RNA-Seq analysis	Yes	No	Yes
Fastq utilities	Yes	No	Yes
Command line interface	Yes	No	Yes