Table 2.

Benchmark (https://lemortho.ezlab.org) of popular orthology methods versus revised RefOGs (37,38)

					RefOGs
Method	Num. of OGs (RefOGs = 70)	RefOGs with F1 ≥ 85%	RefOGs with precision ≥ 85%	RefOGs with recall ≥ 85%	Exact	Akin	Split refOGs (events)
OrthoLoger	164	61	58	59	20	18	12(50)
OrthoFinder	147	58	57	64	17	26	15(41)
SonicParanoid	163	62	63	62	19	23	11(53)
OrthoMCL	207	56	62	51	9	16	18(54)
OMA	325	56	65	27	4	0	16(62)