Table 1.

SEdb 2.0 data content compared with SEdb 1.0

Function type	Data type/specific function	SEdb 1.0	SEdb 2.0	Fold increase
Interaction table/annotation	Species	Human	Human, Mouse	2
	Sample	542	2670	∼5
	Super-enhancer	331 601	1 717 744	∼5
	Common SNP	38 063 729	79 078 255	∼2
	eQTL	31 080 511	61 786 727	∼2
	Enhancer	14 867 092	79 709 120	∼5
	Chromatin accessibility region	No	Yes	New
	Methylation site	No	Yes	New
	Chromatin interactions region	No	Yes	New
	TAD	No	Yes	New
	TF ChIP-seq	No	Yes	New
	TF motif scan analysis	No	Yes	New
Genome browser	Reference genome	hg19	hg38, hg19 mm10, mm39	4
	Super-enhancer	Yes	Yes	–
	Super-enhancer element	Yes	Yes	–
	TFBS by ChIP-seq	No	Yes	New
	Methylation site	No	Yes	New
	TAD	No	Yes	New
	SNP	Yes	Yes	–
	Common SNP	Yes	Yes	–
	Risk SNP	Yes	Yes	–
	TFBS conserved	Yes	Yes	–
	CRISPR/Cas9 target site	Yes	Yes	–
	DHS	Yes	Yes	–
	Enhancer	Yes	Yes	–
	Conservative score	Yes	Yes	–
Analysis functions	Differential-Overlapping-SE analysis	No	Yes	New
	SE-based TF–Gene analysis	No	Yes	New
	Gene-SE analysis	Yes	Yes	–
	SNP-SE analysis	Yes	Yes	–
	Overlap analysis	Yes	Yes	–
	Region analysisa	Yes	Yes	–

^aExternal link to GREAT.