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. 2022 Oct 16;51(D1):D631–D637. doi: 10.1093/nar/gkac883

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© The Author(s) 2022. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — SIGNOR 3.0, new web resource and functionalities. (A) The SIGNOR 2.0 and 3.0 home pages. (B) SIGNOR 3.0 provides direct access to related projects: DisNor (14), CancerGeneNet (15), Myo-REG (16) and the COVID-19 (17). (C) The disease browser builds causal network connecting genes that have been found to be mutated in patients affected by a specific disease (GDA, nodes in yellow), as provided by the DisGeNET (20), IntOGen (21) and Cancer Gene Census (22) resources. (D) Newly developed ‘advanced methods’ allow the user to browse for direct connections linking custom lists of input and output proteins. (E) Newly developed ‘advanced methods’ allow the user to filter interactions annotated to a given tissue, cell type or system.