Table 5.
Correlations between ultrasound shear wave elastography measurements and second harmonic imaging microscopy (SHIM) collagen measurements, including by individual bowel wall histological layer, from resected pediatric strictured ileal segments (n=18)
| Histological layer | Median BW SWS (0%) | Median BW SWS (10%) |
Median BW SWS (20%) | Median RLQ SWS (0%) |
Median RLQ SWS (10%) |
Median RLQ SWS (20%) |
|---|---|---|---|---|---|---|
| Entire bowel wall | −0.44 [−0.76–0.05] (p=0.07) |
−0.10 [−0.55–0.40] (p=0.69) |
−0.25 [−0.65–0.26] (p=0.33) |
−0.18 [−0.60–0.33] (p=0.48) |
−0.01 [−0.49–0.47] (p=0.96) |
0.11 [−0.39–0.56] (p=0.66) |
| Mucosa | 0.13 [−0.37–0.58] (p=0.60) |
0.15 [−0.36–0.58] (p=0.56) |
0.22 [−0.29–0.63] (p=0.39) |
0.31 [−0.20–0.69] (p=0.21) |
0.44 [−0.05–0.76] (p=0.07) |
0.41 [−0.09–0.74] (p=0.09) |
| Submucosa | −0.05 [−0.52–0.44] (p=0.84) |
0.07 [−0.43–0.53] (p=0.79) |
−0.031 [−0.49–0.47] (p=0.96) |
0.15 [−0.36–0.58] (p=0.56) |
0.23 [−0.28–0.64] (p=0.35) |
0.26 [−0.25–0.66] (p=0.29) |
| Muscularis propria, inner layer | 0.31 [−0.22–0.69] (p=0.23) |
0.21 [−0.31–0.64] (p=0.41) |
0.25 [−0.27–0.66] (p=0.33) |
0.39 [−0.12–0.74] (p=0.12) |
0.43 [−0.08–0.76] (p=0.09) |
0.38 [−0.14–0.73] (p=0.14) |
| Muscularis propria, outer layer | 0.20 [−0.39–0.67] (p=0.50) |
0.28 [−0.31–0.71] (p=0.33) |
−0.002 [−0.54–0.54] (p>0.99) |
0.22 [−0.37–0.68] (p=0.45) |
0.34 [−0.25–0.75] (p=0.23) |
0.21 [−0.37–0.68] (p=0.47) |
95% confidence intervals are in brackets, and P-values are in parentheses
BW bowel wall, RLQ right lower quadrant, SWS shear wave speed