Table 1.

Annotation data in FerrDb V2

Data set	Primary category	Secondary category	Description
Driver	Regulator	Gene	A gene that promotes ferroptosis
Suppressor	Regulator	Gene	A gene that prevents ferroptosis
Marker	Regulator	Gene	A gene that indicates ferroptosis occurrence
Unclassified gene	Regulator	Gene	A gene that is associated with ferroptosis, but its regulatory role is unclear
Inducer	Regulator	Substance	A chemical entity that can cause ferroptosi
Inhibitor	Regulator	Substance	A chemical entity that can restrict ferroptosis
Ferroptosis-disease association	Association	Ferroptosis-disease association	Ferroptosis has two opposite effects on disease: aggravating an illness or alleviating an unpleasant situation

NB The table is adapted from the article of Zhou and Bao (13), with approval from the copyright holder.