TABLE 1.
BMISDS change | ||||
---|---|---|---|---|
All patients | ||||
No. (%) | Mean | Median | p value a | |
Overall population | 765 | 0.64 | 0.61 | |
Age group (years) | ||||
Age 2–5.9 | 464 (60.7) | 0.85 | 0.83 | |
Age 6–9.9 | 158 (20.7) | 0.46 | 0.48 | <.001 |
Age 10–17.9 | 143 (18.7) | 0.15 | 0.10 | |
Gender | ||||
Male | 417 (54.5) | 0.62 | 0.59 | .48 |
Female | 348 (45.5) | 0.67 | 0.64 | |
Weight group at diagnosis | ||||
Underweight | 35 (4.6) | 2.27 | 2.08 | |
Healthy weight | 640 (83.7) | 0.65 | 0.65 | <.001 |
Overweight | 74 (9.7) | −0.01 | 0.04 | |
Obese | 16 (2.1) | −0.15 | −0.13 | |
Risk group | ||||
Standard risk treatment | 410 (53.6) | 0.69 | 0.64 | |
Intermediate risk treatment | 287 (37.5) | 0.67 | 0.63 | <.001 |
High risk treatment | 68 (8.9) | −0.09 | 0.13 | |
Immunophenotype | ||||
B‐cell ALL | 668 (87.3) | 0.67 | 0.63 | .03 |
T‐cell ALL | 97 (12.7) | 0.43 | 0.49 | |
Induction therapy | ||||
Prednisolone induction | 621 (81.2) | 0.68 | 0.68 | .03 |
Dexamethasone induction | 144 (18.8) | 0.46 | 0.47 | |
WBC at diagnosis | ||||
WBC <50 × 109/L | 602 (78.7) | 0.67 | 0.63 | |
WBC 50–100 × 109/L | 73 (9.6) | 0.63 | 0.59 | .06 |
WBC >100 × 109/L | 90 (11.8) | 0.41 | 0.51 | |
CNS status at diagnosis | ||||
CNS negative ALL | 741 (96.9 | 0.64 | 0.61 | .48 |
CNS positive ALL | 24 (3.1) | 0.49 | 0.54 |
Abbreviations: ALL, acute lymphoblastic leukemia; CNS, central nervous system; WBC, white blood cell count.
Qui‐square test, independent t tests, and one‐way ANOVA are based on mean.