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The figure is a simplified representation of the di‐iron catalytic active site in the stearoyl‐ACP desaturase homodimer. The red circles highlight the two irons in their reduced form (Fe2+‐Fe2+) present in the active site, which are coordinated with glutamate and histidine residues and a molecule of water. This is fundamental for the activity of the desaturases—J. Biol. Chem. 284, 18559–18563(2011). 32
