FIGURE 1.

Retinol treatment induces keratinocyte proliferation and expression of proteins required for skin barrier function. (a) Representative images showing immunostaining for keratinocyte proline‐rich protein [KPRP], filaggrin and e‐cadherin/Ki67 staining within the epidermis. (b) Quantification of epidermal thickness, (c) filaggrin abundance, (d) melanin distribution and (e) Ki67 expression are shown. Statistical significance for differences between treatments compared with the baseline control was assessed by repeated‐measures one‐way ANOVA followed by a Dunnett's multiple comparison test (*p < 0.05, **p < 0.01).