TABLE 2.

Application regimen in 6‐week tolerance study

Week	Application frequency	Application number
1	Twice a week on non‐consecutive evenings	Application 1+2
2	Twice a week on non‐consecutive evenings	Application 3+4
3	Three times a week on non‐consecutive evenings	Application 5–7
4	Three times a week on non‐consecutive evenings	Application 8–10
5	Every evening	Application 11–17
6	Every evening	Application 18–24