TABLE 1.
Summary of results from genetic analysis of all OL brush samples with matched biopsy sample
| ID | Dysplasia | Diff. dysp. | CNAs | Mutations | Genetic event | |||
|---|---|---|---|---|---|---|---|---|
| Biopsy | Brush | Biopsy | Brush | Biopsy | Brush | |||
| LP09 | None | Yes | 12 | 2 | 5 | 2 | Yes | Yes |
| LP10 | None | Yes | 2 | 1 | 0 | 0 | Yes | Yes |
| LP11 | None | No | 0 | 0 | 2 | 0 | Yes | No |
| LP12 | None | No | 2 | 4 | 1 | 2 | Yes | Yes |
| LP13 | Mild | Yes | 4 | 7 | 1 | 1 | Yes | Yes |
| LP14 | Mild | No | 0 | 0 | 0 | 0 | No | No |
| LP15 | None | No | 0 | 0 | 0 | 0 | No | No |
| LP17 | None | Yes | 0 | 0 | 0 | 0 | No | No |
| LP19 | Mild | No | 2 | 3 | 1 | 2 | Yes | Yes |
| LP20 | None | No | 1 | 1 | 0 | 0 | Yes | Yes |
| LP21 | None | No | 1 | 1 | 0 | 2 | Yes | Yes |
| LP22 | None | No | 0 | 0 | 0 | 0 | No | No |
| LP25 | Moderate | No | 6 | 5 | 5 | 5 | Yes | Yes |
| LP26 | None | No | 2 | 3 | 5 | 5 | Yes | Yes |
| LP27 | Mild | No | 18 | 0 | 2 | 1 | Yes | Yes |
| LP28 | Mild | No | 2 | 9 | 0 | 4 | Yes | Yes |
| LP29 | ‐ | ‐ | 5 | 8 | 2 | 1 | Yes | Yes |
| LP31 | None | No | 2 | 2 | 3 | 4 | Yes | Yes |
| LP32 | ‐ | ‐ | 1 | 0 | 4 | 0 | Yes | No |
| LP33 | Moderate | No | 0 | 1 | 5 | 1 | Yes | Yes |
| LP35 | None | Yes | 0 | 0 | 0 | 0 | No | No |
| LP39 | Severe | Yes | 22 | 3 | 3 | 1 | Yes | Yes |
| LP40 | None | No | 0 | 1 | 5 | 8 | Yes | Yes |
| LP41 | None | No | 0 | 0 | 0 | 0 | No | No |
| LP42 | None | No | 0 | 0 | 0 | 0 | No | No |
| LP43 | Moderate | No | 2 | 5 | 1 | 1 | Yes | Yes |
| LP45 | Mild | No | 1 | 0 | 0 | 0 | Yes | No |
| LP46 | None | No | 10 | 8 | 0 | 0 | Yes | Yes |
| LP47 | None | Yes | 14 | 4 | 0 | 2 | Yes | Yes |
| LP48 | None | No | 2 | 0 | 1 | 0 | Yes | No |
| LP49 | None | No | 0 | 0 | 0 | 0 | No | No |
| LP51 | None | Yes | 0 | 0 | 0 | 0 | No | No |
| LP52 | None | Yes | 3 | 4 | 0 | 0 | Yes | Yes |
| LP53 | None | Yes | 2 | 2 | 2 | 3 | Yes | Yes |
| LP56 | None | Yes | 0 | 0 | 1 | 1 | Yes | Yes |
| LP57 | Mild | No | 3 | 3 | 0 | 0 | Yes | Yes |
| LP58 | None | No | 1 | 0 | 0 | 0 | Yes | No |
| LP59 | None | No | 14 | 16 | 3 | 2 | Yes | Yes |
| LP65 | Moderate | No | 11 | 22 | ‐ | ‐ | Yes | Yes |
| LP67 | None | Yes | 0 | 18 | 0 | ‐ | No | Yes |
| LP68 | None | Yes | 0 | 0 | 1 | 1 | Yes | Yes |
Note: Biopsy material and brushed cells from matching OL lesions were analyzed for presence of mutations and CNAs. Number of CNAs is subject to the segmentation algorithm. This table also reports the grade of dysplasia and the presence of differentiated dysplasia observed in the biopsy. Presence of either mutations or CNAs is summarized as the detection of any genetic event in the last two columns.