Table 4.

Summary of dinuclear and trinuclear copper(II) complexes with better IC₅₀ values (μM) in different cell lines.

Compound	Metal geometry	Exposure time [h]	Cell lines	IC50 value [μg mL−1]	Main feature	Ref.
Cu‐50	Square planar	24 48	HeLa	16.9 7.1	Anticancer activity depends on the lipophilic character conferred by the tert‐butyl groups, being absorbed more efficiently in the cell	[76]