Table 8.
Summary of vanadium(V) complexes coordinated to O N O ligands with better IC50 values (μM) in different cell lines.
Compound |
Metal geometry |
Exposure time [h] |
Cell lines |
IC50 value [μM] |
Main feature |
Ref. |
---|---|---|---|---|---|---|
V‐45 |
Octahedral |
48 |
A‐2780 |
5.7±1.6 |
Anticancer activity depends on chirality and the presence of the 8‐hydroxyquinoline‐derived co‐ligand |
[98] |
V‐47 |
square pyramidal |
72 |
Hep‐2 |
2.45±0.07 |
Anticancer activity depends on chirality |
[99] |
V‐48 |
1.77±0.04 |