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. 2022 Sep 23;17(20):e202200367. doi: 10.1002/cmdc.202200367

Table 9.

Summary of zinc(II) complexes coordinated to O N O ligands with better IC50 values (μM) in different cell lines.

Compound

Metal geometry

Exposure time [h]

Cell lines

IC50 value [μM]

Main feature

Ref.

Zn‐06

Octahedral

48

HeLa MCF‐7 A‐2780 V‐79

4.58±1.0 3.04±1.2 1.73±0.4 4.06±0.55

Anticancer activity depends on the presence of the co‐ligand, in this case diphphen

[102]

Zn‐10

NR

HeLa K‐562

14.28 25.07

Anticancer activity depends on the nuclearity and geometry of the complexes

[105]