Table 9.
Summary of zinc(II) complexes coordinated to O N O ligands with better IC50 values (μM) in different cell lines.
|
Compound |
Metal geometry |
Exposure time [h] |
Cell lines |
IC50 value [μM] |
Main feature |
Ref. |
|---|---|---|---|---|---|---|
|
Zn‐06 |
Octahedral |
48 |
HeLa MCF‐7 A‐2780 V‐79 |
4.58±1.0 3.04±1.2 1.73±0.4 4.06±0.55 |
Anticancer activity depends on the presence of the co‐ligand, in this case diphphen |
[102] |
|
Zn‐10 |
NR |
HeLa K‐562 |
14.28 25.07 |
Anticancer activity depends on the nuclearity and geometry of the complexes |
[105] |