Table 11.
Summary of manganese(II/III) complexes coordinated to O N O ligands with better IC50 values (μM) in different cell lines.
|
Compound |
Metal geometry |
Exposure time [h] |
Cell lines |
IC50 value [μM] |
Main feature |
Ref. |
|---|---|---|---|---|---|---|
|
Mn‐07 |
Octahedral |
48 |
HeLa |
10.54±1.02 |
Anticancer activity depends on metal ion types, chirality and nuclearity |
[85] |
|
Mn‐08 |
A‐549 MDA‐MB‐231 |
11.59±1.06 10.78±1.03 |
Anticancer activity depends on the chirality and structure of the ligands |
[113] |
||
|
Mn‐09 |
7.24±0.86 15.66±1.20 |
|||||
|
Mn‐10 |
A‐549 MDA‐MB‐231 Hep‐G2 |
10.69±1.03 6.14±0.79 21.85±1.34 |
||||
|
Mn‐11 |
MDA‐MB‐231 Hep‐G2 |
18.44±1.279 25.90±1.41 |