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. 2022 Sep 23;17(20):e202200367. doi: 10.1002/cmdc.202200367

Table 16.

Summary of tantalum(V) complexes coordinated to O N O ligands with better IC50 values (μM) in different cell lines.

Compound

Metal geometry

Exposure time [h]

Cell lines

IC50 value [μM]

Main feature

Ref.

Ta‐01

Polyhedral

24

A‐2780 A‐2780R HOS MRC‐5

8.6±0.9 16.0±0.3 16.8±2.0 >50

The anticancer activity depends on the metal, in this case, tantalum

[134]