Table 16.
Summary of tantalum(V) complexes coordinated to O N O ligands with better IC50 values (μM) in different cell lines.
Compound |
Metal geometry |
Exposure time [h] |
Cell lines |
IC50 value [μM] |
Main feature |
Ref. |
---|---|---|---|---|---|---|
Ta‐01 |
Polyhedral |
24 |
A‐2780 A‐2780R HOS MRC‐5 |
8.6±0.9 16.0±0.3 16.8±2.0 >50 |
The anticancer activity depends on the metal, in this case, tantalum |
[134] |