Table 19.

Summary of vanadium(V) and molybdenum(V) complexes coordinated to O N N ligands with better IC₅₀ values (μM) in different cell lines.

Compound	Metal geometry	Exposure time [h]	Cell lines	IC50 value [μM]	Main feature	Ref.
V‐52	Octahedral	24	Caco‐2	0.0279	The anticancer activity depends on the lipophilic character conferred by the symmetry of the compound	[158]
Mo‐03	Square pyramidal	48	MCF‐7 HCT‐15 HaCaT	11.13±0.65 32.20±0.92 200.74±0.12	The anticancer activity depends on the binding capacity of the complex with DNA, influenced by the absence of substituents in the ligand	[159]