TABLE 3.
Prevalence per million persons of Langerhans cell histiocytosis in England on 31 December 2019
| N (%) a of people diagnosed with LCH in 2013–2019 and still alive at the end of 2019 | Prevalence (95% CI) | |
|---|---|---|
| Age on 31 December 2019, years | ||
| Infants (<1) | 2 (0) | 3.23 (0.39–11.67) |
| 1–14 | 280 (50) | 29.25 (25.92–32.88) |
| 15–29 | 81 (14) | 7.80 (6.20–9.70) |
| 30–44 | 66 (12) | 6.02 (4.66–7.66) |
| 45–59 | 79 (14) | 6.99 (5.54–8.72) |
| ≥60 | 52 (9) | 3.86 (2.88–5.06) |
| Children (<15) | 282 (50) | 27.67 (24.53–31.09) |
| Adults (≥15) | 278 (50) | 6.03 (5.34–6.78) |
| Overall | 560 (100) | 9.95 (9.14–10.81) |
| Sex | ||
| Female | 245 (44) | 8.61 (7.56–9.76) |
| Male | 315 (56) | 11.32 (10.10–12.64) |
| Deprivation quintile | ||
| 1 – least deprived | 101 (18) | 9.27 (7.55–11.26) |
| 2 | 94 (17) | 8.46 (6.83–10.35) |
| 3 | 98 (18) | 8.58 (6.96–10.45) |
| 4 | 130 (23) | 11.23 (9.38–13.33) |
| 5 – most deprived | 137 (24) | 12.16 (10.21–14.37) |
| Region | ||
| North East | 26 (5) | 9.74 (6.36–14.27) |
| North West | 62 (11) | 8.45 (6.48–10.83) |
| Yorkshire/Humber | 53 (9) | 9.63 (7.21–12.60) |
| East Midlands | 37 (7) | 7.65 (5.39–10.55) |
| West Midlands | 77 (14) | 12.98 (10.24–16.22) |
| East of England | 50 (9) | 8.02 (5.95–10.57) |
| London | 80 (14) | 8.93 (7.08–11.11) |
| South East | 104 (19) | 11.33 (9.26–13.73) |
| South West | 71 (13) | 12.62 (9.86–15.92) |
Abbreviations: CI, confidence interval; LCH, Langerhans cell histiocytosis. a :Percentages might not total 100% due to approximation.