FIG. 3.

Neutralization of C. pneumoniae infectivity with MAb GZD1E8. In the presence of complement, MAb GZD1E8 resulted in a 10,000-fold reduction of IFU at concentrations of 10 and 100 μg/ml. Incubation of C. pneumoniae with the GZD1E8 MAb in the presence of heat-inactivated guinea pig sera (HIC) did not result in a reduction of IFU. This neutralization assay was additionally performed with anti-chlamydial Hsp60 MAb A57-B9 and anti-rickettsial MAb 8-13A4A10. Most of the standard error bars are contained within the symbols.