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. 2022 Sep 13;23(20):e202200345. doi: 10.1002/cbic.202200345

Table 1.

IC50 values for microviridin J and microviridin B derivatives.

Trypsin inhibition assay

IC50 [μM]

Elastase inhibition assay

IC50 [μM]

MvJ_CPcy3 (1)

1.09±0.09

MvB_CPcy3 (4)

0.33±0.02

MvJ_CP_N(Bio)cy3 (2)

3.53±0.30

MvB_CP_N(Bio)cy3 (5)

1.24±0.64

MvJ_CP_N(Prop)cy3 (3)

1.64±0.12

MvB_CP_N(Dansyl)cy3 (6)

28.05±7.17