Figure 2.

Expanded region of the 11+ charge state of a buffered mixture of TPR2AB with four selected binding fragments, F8 (A), F17 (B), F21 (C) and F 22 (D). Binding ratio was estimated based on the relative abundance of apo TPR2AB (m/z 3618.8, [M+11H]11+) and TPR2AB‐fragment complex and shown in Tables 1 and 2. Fragment binding was confirmed based on the Δ m/z from the apo TPR2AB peak.