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. 2022 Sep 10;26(10):2176–2187. doi: 10.1002/ejp.2029

FIGURE 5.

FIGURE 5

Correlation of conditioned pain modulation (CPM) capacity with neuropathic pain characteristics. The sham‐controlled CPM capacity (effect by the sham water bath subtracted from effect by the cold water bath) is presented as the change in pressure pain thresholds in percent in the parallel CPM paradigm. Negative changes depict inhibition, positive changes depict facilitation. (a) Positive correlation of CPM magnitude with spontaneous neuropathic pain intensity. (b) No significant correlation of CPM magnitude with neuropathic pain extent. (c) Positive correlation of the CPM magnitude during the cold bath only with spontaneous neuropathic pain intensity. Abbreviation: NRS, numeric rating scale.