Figure 3.

The TEA project will aim to identify what current tools and what additional tool development will be necessary to change the agrochemical testing paradigm quickly and efficiently. The toolkit can be considered as ranging from the current guideline studies in model species where we observe toxicity, to a future state where we have a suite of sufficiently descriptive mechanistic quantitative multiscale models that comprehensively covers the entirety of regulatory endpoints of concern and is rapidly informed by chemical specific data. It is anticipated that mechanistic model‐based approaches will permit more rapid and sustained high quality decision making. However, the current state of the science does not provide similar levels of technological readiness across this full spectrum of tools. Nevertheless, the goal is to make practical improvements to safety assessment and not delay until we create a theoretically perfect system. Therefore, the identification of existing NAMs that both accelerate the speed to decisions, and maintain or improve on the current quality of those decisions, is an important early goal of the project. This output represents the ‘good enough toolkit’, where we can efficiently and confidently implement a sufficiently rapid decision‐making process.