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KDM5 inhibitors activate tumor cell intrinsic STING and suppress tumor growth. (A) Western blot showing the induction of STING expression after CPI-455 treatment in MC38, and CT26 cells. (B) In vivo tumor growth curves of control or STING knockout MC38 cells with or without CPI-48 treatment. N = 10. * ** P < 0.001. NS: not significant.
