Table 3.
Comparison of EOS- Patients’ Profile According to Allergic Profile: ALL+ Vs ALL
| Characteristics: (N, (%) | ALL+ | ALL- | p-value | |
|---|---|---|---|---|
| N=293 | N=132 | |||
| Sex | Male | 90 (30.7%) | 51 (38.6%) | 0.11 |
| Female | 203 (69.3%) | 81 (61.4%) | ||
| Age (years) | 18–40 | 54 (18.4%) | 12 (9.1%) | <0.01 |
| 40–60 | 144 (49.1%) | 44 (33.3%) | ||
| ≥60 | 95 (32.4%) | 76 (57.6%) | ||
| Body mass index (kg/m²) | <25 | 109 (37.2%) | 40 (30.3%) | 0.03 |
| 25–30 | 94 (32.1%) | 60 (45.5%) | ||
| ≥30 | 90 (30.7%) | 32 (24.2%) | ||
| Smoking status | Smoker | 36 (12.3%) | 13 (9.8%) | 0.24 |
| Former smoker | 81 (27.6%) | 47 (35.6%) | ||
| Never smoker | 176 (60.1%) | 72 (54.5%) | ||
| Personal history of atopy | Yes | 264 (91.3%) | 34 (26.6%) | <0.01 |
| ENT disease | Yes | 170 (58.0%) | 70 (53.4%) | 0.38 |
| Chronic rhinitis | Yes | 134 (46.0%) | 45 (34.6%) | 0.03 |
| Chronic rhinosinusitis | Yes | 80 (28.0%) | 32 (24.4%) | 0.45 |
| Polyposis | Yes | 32 (11.6%) | 24 (18.6%) | 0.06 |
| Other comorbidity reported | Yes | 228 (77.8%) | 104 (78.8%) | 0.82 |
| GERD | Yes | 138 (47.4%) | 51 (39.8%) | 0.15 |
| High blood pressure | Yes | 76 (26.1%) | 44 (33.3%) | 0.13 |
| Diabetes | Yes | 25 (8.6%) | 18 (13.7%) | 0.11 |
| Sleep apnea syndrome | Yes | 30 (11.5%) | 19 (16.0%) | 0.23 |
| Osteoporosis | Yes | 32 (11.7%) | 19 (15.2%) | 0.33 |
| Anxiety | Yes | 135 (46.6%) | 54 (40.9%) | 0.28 |
| Depression | Yes | 53 (18.2%) | 24 (18.2%) | 0.99 |
Notes: ALL- group included patients with negative results to allergic sensitization tests; ALL+ group included patients with positive results to allergic sensitization tests. EOS- was defined by blood eosinophil count <300 G/l. Missing data were not replaced; percentages are calculated on available data.
Abbreviations: ALL, allergic (asthma); ENT, Ear, Nose, and Throat; EOS, Eosinophil; G/l, Giga per liter; GERD, Gastroesophageal reflux disease; kg/m²: Kilogram per square meter; N, Number.