Table 2:
Bone Parameters at Distal Radius as Assessed by High Resolution Peripheral Quantitative Computed Tomography (HR-pQCT) in Females with Obesity (OB) and Normal-weight Healthy Controls (HC)
| OB N = 33 |
HC N = 32 |
P-value | P-value adjusted for age and race | |
|---|---|---|---|---|
| Total vBMD (mgHA/cm3) | 368.33 ± 65.88 | 319.85 ± 53.14 | 0.002 | 0.0003 |
| Trabecular vBMD (mgHA/cm3) | 202.86 ± 35.21 | 177.93 ± 35.36 | 0.006 | 0.005 |
| Cortical vBMD (mgHA/cm3) | 850.67 ± 45.26 | 828.61 ± 63.84 | 0.11 | 0.005 |
| Total bone area (mm2) | 269.05 ± 58.00 | 262.47 ± 38.21 | 0.59 | 0.92 |
| Cortical thickness (mm) | 0.93 ± 0.19 | 0.76 ± 0.18 | 0.0004 | <0.0001 |
| Cortical area/Total area | 0.24 ± 0.07 | 0.20 ± 0.06 | 0.01 | 0.002 |
| Cortical porosity (%) | 1.26 ± 0.55 | 0.87 ± 0.50 | 0.004 | 0.018 |
| Impact Force (N) | 2961 ± 239 | 2076 ± 125 | <.0001 | <0.0001 |
| Failure Load (N) | 4610.93 ± 769 | 3901.52 ± 641 | 0.0002 | 0.0005 |
| Load-to-Strength Ratio | 0.69 ± 0.11 | 0.54 ± 0.08 | <.0001 | <.0001 |
Data presented as Mean ±SD. Bold denotes significant p-value. Between group differences were compared using the Student t-test for parametric data and the 2-sample Wilcoxon rank sum test for non-parametric data