Fig. 4.

Effect of fibrosis and recovery on the plasma degradome. Plasma peptides were measured by LC-MS/MS, as described in experimental procedures and compared naive control mice (Log2FC). Panel A:the pattern of changes in peptides over the course of the recovery period that were increased at 28 days. The panels depict the upper quadrants of peptides summarized in Panel B. Panel B: compares the change in peptides after 28 days of recovery, versus those at 1 day. Panel C:Venn diagram comparing the peptides increased at 28 days of recovery to those increased at 1 day of recovery. Box and whisker plots depict the range, median and interquartile range of the changes of the degraded proteins over the period of recovery (Panel A).