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. 2022 Dec 20;4(1):100364. doi: 10.1016/j.xinn.2022.100364

Figure 4.

Figure 4

The specific accessible chromatin regions of ESCs, ME cells, and DE cells reveal the cell states of ES-FOS-KD cells, ES-HSF1-OE cells, and ES-MYCN-OE cells

(A) t-SNE plot shows the distribution of all samples on the basis of ATAC-seq.

(B) The heatmap shows the Pearson correlation of all samples on the basis of ATAC-seq.

(C) Heatmap of ATAC-seq data around the peak center of ES-generated binding sites, ME-generated binding sites, and DE-generated binding sites. The numbers of peaks for ESCs, ME cells, and DE cells are also shown.

(D) Profile plot of ES-specific binding site and ME-specific binding site showed in ES-FOS-KD cells, ES-HSF1-OE cells, and ES-MYCN-OE cells and ME cells.