Fig. 3.

Schematic representation of the different high-throughput tools for miRNAs detection in PCa. MiRNAs may be extracted from various sources such as tissue biopsies, blood, urine, and semen. Several high-throughput strategies exist to detect miRNAs. They range from qRT-PCR, microarray, and next-generation sequencing to NanoString nCounter-based methods. These tools are useful to identify the miRNAs with a dysregulated profile which may consequently serve as biomarkers for PCa diagnosis, prognosis, and response to therapy. Abbreviations PCa; prostate cancer, FFPE; formalin-fixed paraffin-embedded, miRNA; microRNA, qRT-PCR; quantitative real-time reverse-transcription-polymerase chain reaction.