TABLE 1.
Growth of BCG in WT and SCID mice
| Mouse group | Log10 CFU of BCGa in:
|
||
|---|---|---|---|
| Liver | Spleen | Lung | |
| WT | 5.533 ± 0.11 | 5.45 ± 0.09 | 4.88 ± 0.19 |
| SCID | 6.61 ± 0.36 | 6.82 ± 0.24 | 6.29 ± 0.23 |
| WT + HC2 | 7.31 ± 0.27 | 6.72 ± 0.06 | 5.55 ± 0.02 |
| SCID + HC | 8.66 ± 0.58 | 8.39 ± 0.24 | 7.03 ± 0.27 |
a
Mean ± standard deviation of results for five mice per group on day 30 of infection.
b
WT and SCID mice were given 1.25 mg of HC acetate on days 15, 17, 20, and 23 of infection.
c
Differences among means per given organ were highly significant (P < 0.001) by Students's t test.