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(A to C) Activation of caspase-8 (A), -9 (B), and -3 (C) in H. pylori NGY1281-infected AGS cells. Effects of the inhibitors of caspase-8 and -9 were also examined. (D) Dose-dependent activation of caspase-8, -9, and -3 by H. pylori membrane fraction at 24 h. AGS cells were exposed to the H. pylori membrane preparation at the indicated protein concentration for 24 h. Bars represent mean values ± SD from three experiments.
