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MitomiR dysregulation as signature of FD. MitomiRs are significantly dysregulated in FD. The altered miRs are involved in fundamental mechanisms required for the maintenance of mitochondrial homeostasis, including ETC expression and assembly, mitochondrial metabolism, mitogenesis, mitochondrial oxidative damage and apoptosis. This emphatic pattern could represent a new FD footprint. Cyt-C, Cytochrome C; ETC, electron transport chain; FD, Fabry disease.
