Figure 5. Current bacterial natural products and the encoded potential for others.

(A) The number of compounds per bacterial phylum as found in the NPAtlas_v2021_08. Inset shows phyla with fewer than 200 compounds. Phyla are distributed as shown in the legend. Some phyla have since been subdivided and are not representative of the tree in part B (e.g. Myxococcota (“Myxobacteria”) is found in the NPAtlas within the phylum Proteobacteria). The total number of compounds includes analogues of the same compound family and does not necessarily represent distinct chemical scaffolds. Source data in Appendix Tables S10 and S11. (B) Representation of the biosynthetic potential of bacterial phyla based on the number of genomes per phylum and the estimated number of gene cluster families. This number estimates the number of different compounds possible from members of these phyla. Part (B) reproduced from Garvriilidou et al with permission from Springer Nature.Source data are available online for this figure.