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Micro CT from a SCID mouse (Panel A), nonsupplemented PXB-mouse (Panel B) and a PXB-mouse supplemented with ascorbic acid (AA) (Panel C). Nonsupplemented PXB-mice had less trabecular bone (red arrows), resulting in physeal fractures in some mice (bottom middle image). Vitamin C supplementation in PXB-mice was associated with bone structure similar to that of SCID controls.
