Table 2.
Adverse Event |
No. of Patients (n = 8) | Adverse Event |
No. of Patients (n = 8) | ||||
---|---|---|---|---|---|---|---|
Garde 2 | Grade 3 | Grade 4 | Garde 2 | Grade 3 | Grade 4 | ||
Probably related | Respiratory | ||||||
Central nervous system | 0 | 0 | 0 | Atelectasis | 0 | 0 | 0 |
Headache | 0 | 1 | 0 | Pain | |||
Seizure | 1 | 0 | 0 | Extremity | 0 | 0 | 0 |
Unrelated | Bone | 0 | 0 | 0 | |||
Hematologic toxic | Myalgia | 4 | 1 | 0 | |||
Anemia | 2 | 0 | 0 | Musculoskeletal | |||
Lymphopenia | 4 | 1 | 0 | Edema, localized | 0 | 0 | 0 |
Neutropenia | 5 | 0 | 0 | Fracture | 0 | 0 | 0 |
Thrombocytopenia | 0 | 0 | 0 | Central nervous system | |||
Nonhematologic toxic | Headache | 1 | 1 | 0 | |||
General | Seizure | 0 | 0 | 0 | |||
Anorexia | 0 | 0 | 0 | Gait disturbance | 0 | 0 | 0 |
Fatigue | 1 | 0 | 0 | Memory impairment | 0 | 0 | 0 |
Somnolence | 1 | 0 | 0 | Tremors | 0 | 0 | 0 |
Weakness | 1 | 0 | 0 | Cerebral edema | 0 | 0 | 0 |
HEENT | Hydrocephalus | 0 | 0 | 0 | |||
Eye paralysis, lateral | 0 | 0 | 0 | Infectious | |||
Gastrointestinal | Urinary tract infection | 0 | 0 | 0 | |||
Nausea | 0 | 0 | 0 | Laboratory test results | |||
Diarrhea | 0 | 0 | 0 | Elevated ALT | 0 | 0 | 0 |
Constipation | 0 | 0 | 0 | Elevated AST | 0 | 0 | 0 |
Vomiting | 0 | 0 | 0 | Hyperbilirubinemia | 0 | 0 | 0 |
Cardiac | Hyperkalemia | 0 | 0 | 0 | |||
Bradycardia | 0 | 0 | 0 | Hypernatremia | 0 | 0 | 0 |
Hyponatremia | 0 | 0 | 0 |