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. 2023 Jan 9;14:7. doi: 10.1186/s40104-022-00801-4

Table 3.

Effect of N-acyl homoserine lactonase (AHLase) on intestinal morphology1of broilers challenged by Salmonella Typhimurium

Jejunum Ileum
VH, μm CD, μm V/C VH, μm CD, μm V/C
Day 10 NC2 626.22±62.64 106.85±10.07b 5.86±0.59a 485.79±20.67b 117.68±2.74b 4.13±0.18b
PC 573.60±74.18 163.69±30.66a 3.83±0.13b 467.91±28.24b 153.65±30.09a 3.05±0.18c
AHLase 634.42±20.21 109.20±9.54b 5.81±0.19a 547.93±15.57a 114.20±16.40b 4.80±0.14a
P-value 0.352 0.002 < 0.001 0.002 0.037 < 0.001
Day 14 NC2 649.46±40.12 100.85±13.47 6.95±0.41a 562.59±48.41 90.03±2.67b 6.29±0.42a
PC 606.08±126.04 108.85±13.54 5.41±0.28b 526.58±34.54 113.93±6.95a 5.01±0.52b
AHLase 642.24±82.99 88.87±17.50 6.96±0.31a 548.53±13.88 86.64±8.64b 6.54±0.68a
P-value 0.772 0.267 < 0.001 0.386 < 0.001 0.003

a,b Values within a column with unlike superscript letters differ significantly (P < 0.05)

1 VH villus height, CD crypt depth, V/C villus height to crypt depth ratio

2 NC negative control (broilers were free of challenge), PC positive control (broilers were challenged with S. Typhimurium from 7 to 9 d of age); AHLase, PC broilers supplemented with 10 U/g AHLase