Hyperglycemia-mediated increase of PTP1B, VCAM-1 expressions and p65 phosphorylation in aorta of DM rats
(A) Blood glucose levels of rats in the control group and in the diabetic group after the induction of diabetes. (B) Immunohistochemical staining of VCAM-1 in aorta biopsy specimen of rats with corresponding treatments. (C) Immunohistochemical staining of p-p65 in aorta biopsy specimen of rats with corresponding treatments. (D) Immunohistochemical staining of PTP1B in aorta biopsy specimen of rats with corresponding treatments. (E) mRNA level of VCAM-1 in aorta of DM rats. (F) mRNA level of PTP1B in aorta of DM rats. ***P<0.001, ****P<0.0001, n=10/group. Scale bar: 100 μm.