Characteristic | Treated | Untreated |
---|---|---|
Number of women | 33 519 | 10 628 |
Monash IVF Cancer database | 3085 | 4267 |
Monash IVF registry | 30 434 | 6361 |
Age (years) | ||
At entry, median (IQR) | 34 (31–38) | 33 (29–37) |
At follow‐up, median (IQR) | 49 (44–56) | 59 (50–65) |
< 40 years | 3868 (11.5%) | 609 (5.7%) |
40–49 years | 14 126 (42.1%) | 1935 (18.2%) |
50–59 years | 10 831 (32.3%) | 3321 (31.2%) |
60–69 years | 4030 (12.0%) | 4024 (37.9%) |
> 70 years | 664 (2.0%) | 739 (7.0%) |
Aetiology | ||
Aetiology recorded | 20 428 (60.9%) | 6018 (56.6%) |
Unexplained | 5453 [26.7%] | 1781 [29.6%] |
Tubal | 4274 [20.9%] | 2112 [35.1%] |
Endometrial | 2402 [11.8%] | 462 [7.7%] |
Ovarian | 2139 [10.5%] | 378 [6.3%] |
Multiple factors | 3045 [14.9%] | 140 [2.3%] |
Male factor | 1534 [7.5%] | 1036 [17.2%] |
Other | 1581 [7.7%] | 109 [1.8%] |
No aetiology recorded | 13 091 (39.1%) | 4610 (43.4%) |
Stimulated cycles, median (IQR) | 2 (1–4) | — |
1 or 2 | 17 412 (51.9%) | — |
3 or more | 16 107 (48.1%) | — |
Oocytes/cycle, median (IQR) | 7.0 (3–11) | — |
1–5 | 12 913 (38.5%) | — |
6 or more | 17 470 (52.1%) | — |
Missing data | 3136 (9.4%) | — |
Fertility drug type † | ||
Follicle‐stimulating hormone | 29 637 (88.4%) | — |
Hormone replacement therapy | 6267 (18.7%) | — |
Clomiphene citrate | 2419 (7.2%) | — |
Unknown | 3068 (9.1%) | — |
IQR = interquartile range.
Excludes two women (one in each group) for whom registration dates were not reliable.
Women who have ever been treated with drug combination; multiple treatments possible.