Figure 4.

Smar2C2 transcription start site (TSS) compared against ChiP‐corrected annotation.

Previous work has established that genome annotations can be improved by using histone modification ChIP‐seq data to predict the location of TSSs within the genome that might differ significantly from the existing annotation. Smar2C2 TSSs can be used to corroborate the corrected annotations. An example browser shot of the existing annotation, the corrected annotation predicted via ChIP‐seq data and the relevant ChIP‐seq data tracks is shown here. The triangles represent the single base‐pair TSS, as determined by Smar2C2, whereas the red arrows indicate the direction of transcription.