TABLE 3.
Terlipressin | ||||
---|---|---|---|---|
Baseline Parametersb c | nd | Odds Ratio | 95% CI | p |
Baseline ACLF grade (grade 0–2 vs. grade 3) | 320 | 2.435 | 1.260–4.706 | 0.008 |
Baseline serum creatinine | 320 | 0.498 | 0.369–0.674 | <0.001 |
Pooled data were collated from the following Phase III studies: OT-0401, REVERSE, and CONFIRM.
Significant univariate results were added to the model, and stepwise selection was used to obtain the final model.
MELD score was excluded from the multivariate logistic regression model due to the risk of multicollinearity with MELD score components.
This represents the evaluable number of patients for each baseline parameter.
Abbreviations: ACLF indicates acute-on-chronic liver failure; HRS, hepatorenal syndrome; ITT, intent-to-treat; MELD, model for end-stage liver disease; n, number of patients.