Skip to main content
. 2023 Jan 3;7(1):e1307. doi: 10.1097/01.HC9.0000897228.91307.0c

TABLE 3.

Multivariate logistic regression of baseline characteristics on HRS reversal (terlipressin group, pooled ITT population)a

Terlipressin
Baseline Parametersb c nd Odds Ratio 95% CI p
Baseline ACLF grade (grade 0–2 vs. grade 3) 320 2.435 1.260–4.706 0.008
Baseline serum creatinine 320 0.498 0.369–0.674 <0.001
a

Pooled data were collated from the following Phase III studies: OT-0401, REVERSE, and CONFIRM.

b

Significant univariate results were added to the model, and stepwise selection was used to obtain the final model.

c

MELD score was excluded from the multivariate logistic regression model due to the risk of multicollinearity with MELD score components.

d

This represents the evaluable number of patients for each baseline parameter.

Abbreviations: ACLF indicates acute-on-chronic liver failure; HRS, hepatorenal syndrome; ITT, intent-to-treat; MELD, model for end-stage liver disease; n, number of patients.