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. 2023 Jan 3;7(1):e0004. doi: 10.1097/HC9.0000000000000004

FIGURE 1.

FIGURE 1

The total level of m6A and its correlations with clinical indicators in biliary atresia and controls. (A) The total level of m6A in the liver of normal control (NC) (27 cases), cholestasis (CS) (disease control, 28 cases), and biliary atresia (BA) (63 cases). (B) The total level of m6A in BA patients with different stage of fibrosis. (C) The correlation analyses between the total level of m6A and liver function indicators in all patients. (D) The total level of m6A in BA patients with jaundice clearance (JC) or not at 3 months after Kasai portoenterostomy (KPE). (E) The total level of m6A in BA patients with JC or not at 6 months after KPE. (F) The total level of m6A in BA patients with native liver survival (NLS) or not at 2 years after KPE. *p < 0.05, ***p < 0.001, ****p < 0.0001, ns: not significant. Abbreviations: ALB, albumin; ALP, alkaline phosphatase; ALT, alanine aminotransferase; APRI, aspartate aminotransferase-to-platelet ratio index; AST, aspartate aminotransferase; DBIL, direct bilirubin; GGT, gamma-glutamyl transpeptidase; LT, liver transplantation; TBA, total bile acid; TBIL, total bilirubin.