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Schematic representation of hemostasis and thrombosis, and mechanism of action of studied drugs. IIa, activated factor II; IXa, activated factor IX; LMWH, low molecular weight heparin; TF, tissue factor; Va, activated factor V; VIIa, activated factor VII; VIIIa, activated factor VIII; Xa, activated factor X; XIa, activated factor XI; XIIa, activated factor XII
